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Treatment of Gorham-Stout disease with zoledronic acid and interferon-α: a case report and literature review.

Dawn K DK Kuriyama, Sean C SC McElligott, Darryl W DW Glaser, and Karen S KS Thompson

J Pediatr Hematol Oncol 32(8):579-84 (2010) PMID 20962674

Gorham-Stout disease is a rare disease characterized by osteolysis, angiomatosis, and soft-tissue swelling. It is a diagnosis of exclusion and has an unknown etiology. Chylothorax is a common complication of the disease that is associated with a high mortality rate. There is no standard of treatment. We report a case of a 16-year-old female with Gorham-Stout disease and recurrent pleural effusions who was successfully treated with concurrent zoledronic acid and peg-interferon α-2b.

DOI: 10.1097/MPH.0b013e3181edb464
Version: za2963e q8zad q8zbe q8zca q8zd5 q8ze1 q8zfb q8zg0

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