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Efficacy of switching to telbivudine in chronic hepatitis B patients treated previously with lamivudine.

Rifaat Safadi, Qing Xie, Yagang Chen, You-Kuan Yin, Lai Wei, Seong Gyu Hwang, Eli Zuckerman, Ji-Dong Jia, and Patricia Lopez

Liver Int 31(5):667-75 (2011) PMID 21040410

Telbivudine showed greater antiviral suppression than lamivudine in phase II and III clinical trials. Aims: The present phase IIIb, randomized, double-blind, multicentre global trial assessed the antiviral efficacy and safety of telbivudine switch in chronic hepatitis B (CHB) patients who exhibited persistent viraemia under lamivudine therapy.

DOI: 10.1111/j.1478-3231.2010.02360.x
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