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Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse

Björn Reinius, Chengxi Shi, Liu Hengshuo, Kuljeet Sandhu, Katarzyna J Radomska, Glenn D Rosen, Lu Lu, Klas Kullander, Robert W Williams, and Elena Jazin

BMC Genomics 11(1):614 (2010) PMID 21047393

Sexual dimorphism in brain gene expression has been recognized in several animal species. However, the relevant regulatory mechanisms remain poorly understood. To investigate whether sex-biased gene expression in mammalian brain is globally regulated or locally regulated in diverse brain structures, and to study the genomic organisation of brain-expressed sex-biased genes, we performed a large scale gene expression analysis of distinct brain regions in adult male and female mice.

DOI: 10.1186/1471-2164-11-614
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