Advanced search×

Familial defective apolipoprotein B-100 and increased low-density lipoprotein cholesterol and coronary artery calcification in the old order amish.

Haiqing H Shen, Coleen M CM Damcott, Evadnie E Rampersaud, Toni I TI Pollin, Richard B RB Horenstein, Patrick F PF McArdle, Patricia A PA Peyser, Lawrence F LF Bielak, Wendy S WS Post, Yen-Pei C YP Chang, Kathleen A KA Ryan, Michael M Miller, John A JA Rumberger, Patrick F PF Sheedy, John J Shelton, Jeffrey R JR O'Connell, Alan R AR Shuldiner, and Braxton D BD Mitchell

Arch Intern Med 170(20):1850-5 (2010) PMID 21059979

Elevated low-density lipoprotein cholesterol (LDL-C) levels are a major cardiovascular disease risk factor. Genetic factors are an important determinant of LDL-C levels.

DOI: 10.1001/archinternmed.2010.384
Version: za2963e q8za2 q8zb5 q8zc5 q8zde q8ze4 q8zf1 q8zg7
Buy PDF

Similar articles you may find interesting…

  1. Sub-acute administration of (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate induces toxicity and oxidative stress in mice: unexpec...
    Daiane F Meinerz, Bruna Comparsi, and Jeferson L Franco

    SpringerPlus 2(1):182 (2013) PMID 23658858

    The organic tellurium compound (S)-dimethyl 2-(3-(phenyltellanyl) propanamide) succinate (TeAsp) exhibits thiol-peroxidase activity that could potentially offer protection against oxidative stress. However, data from the literature show that tellurium is a toxic agent to rodents. In...
    Buy PDF
  2. Mitochondrial DNA mutations and polymorphisms in asthenospermic infertile men.
    Siwar Baklouti-Gargouri, Myriam Ghorbel, and Leila Ammar-Keskes

    Mol Biol Rep (2013) PMID 23645088

    We performed a systematic sequence analysis of 6 mitochondrial genes (cytochrome oxidase I, cytochrome oxidase II, cytochrome oxidase III, adenosine triphosphate synthase6, ATP synthase8, and cytochrome b] in 66 infertile men suffering from asthenospermia (n = 34) in comparison to normospermic inf...
    Buy PDF
  3. Kif7 is required for the patterning and differentiation of the diaphragm in a model of syndromic congenital diaphragmatic hernia.
    Garry L Coles and Kate G Ackerman

    Proc Natl Acad Sci U S A (2013) PMID 23650387

    We performed a forward genetic screen in mice to identify unique genes, models, and mechanisms of abnormal diaphragm development. We identified a mutant allele of kinesin family member 7 (Kif7), the disorganized diaphragm (dd). Embryos homozygous for the dd allele possess communicating diaphragmatic...
    Buy PDF