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A thrombin generation assay may reduce the need for compression ultrasonography for the exclusion of deep venous thrombosis in the elderly.

Fred J L M FJ Haas, Roger E G RE Schutgens, Cornelis C Kluft, and Douwe H DH Biesma

Scand J Clin Lab Invest 71(1):12-8 (2011) PMID 21073394

The exclusion of deep venous thrombosis (DVT) by pre-test probability (PTP) and D-dimer in the elderly is safe, but has a low specificity. There is increasing interest in the diagnostic role of thrombin generation in patients with thrombosis. We evaluated the value of thrombin generation in the exclusion of DVT, especially in elderly patients.

DOI: 10.3109/00365513.2010.534173
Version: za2963e q8za3 q8zb6 q8zc5 q8zd1 q8zef q8zf4 q8zgb

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