Shining a light on germinal center B cells.
Cell 143(4):503 (2010)
The mechanisms of B cell selection in lymphoid tissues are poorly understood. In this issue, Victora et al. (2010) use imaging of photoactivatable green fluorescent protein to define the movements of B cells in germinal centers and provide evidence that antibody affinity maturation is driven by competition for T cell help.
Copyright © 2010 Elsevier Inc. All rights reserved.
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