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Periodic limb movements in sleep exhibit a circadian rhythm that is maximal in the late evening/early night.

Jeanne F JF Duffy, Alex S W AS Lowe, Edward J EJ Silva, and John W JW Winkelman

Sleep Med 12(1):83-8 (2011) PMID 21093364

Periodic limb movements in sleep (PLMS) show a time-of-night pattern, with most movements at the beginning of the night. Our study aimed to determine whether this pattern is due to an endogenous circadian rhythm, like that in the related movement disorder Restless Legs Syndrome (RLS).

Copyright © 2010 Elsevier Ltd. All rights reserved.

DOI: 10.1016/j.sleep.2010.06.007
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