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Lab-on-a-chip for the isolation and characterization of circulating tumor cells.

Tim Stakenborg, Chengxu Liu, Olivier Henry, Ciara K O'Sullivan, Christian Fermer, Tina Roeser, Marion Ritzi-Lehnert, Sigfried Hauch, Elin Borgen, Nadja Laddach, and Liesbet Lagae

Conf Proc IEEE Eng Med Biol Soc (2010) PMID 21096963

A smart miniaturized system is being proposed for the isolation and characterization of circulating tumor cells (CTCs) directly from blood. Different microfluidic modules have been designed for cell enrichment and -counting, multiplex mRNA amplification as well as DNA detection. With the different modules at hand, future effort will focus on the integration of the modules in a fully automated, single platform.

DOI: 10.1109/IEMBS.2010.5627655
Version: za2963e q8zab q8zb8 q8zc0 q8zdd q8ze2 q8zf3 q8zgc
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