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Synthetic double-stranded RNA stimulates the expression of interferon-inducible protein 10 in human mesothelial cells.

Monika M Merkle, Matthias M Sauter, Andrea A Ribeiro, Thomas T Mussack, Roland R Ladurner, Thomas T Sitter, and Markus M Wörnle

Clin Vaccine Immunol 18(1):176-9 (2011) PMID 21106778 PMCID PMC3019772

Interferon-inducible protein 10 (IP-10) is a chemokine playing an important role in the restriction of viral spread. A time- and dose-dependent increase in IP-10 is found upon activation of viral receptors expressed on mesothelial cells, which provides novel evidence for a link between viral infections and inflammation of serous membranes.

DOI: 10.1128/CVI.00007-10
Version: za2963e q8zad q8zba q8zcd q8zda q8ze7 q8zf2 q8zge
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