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Validated LC-MS/MS methods for the determination of dapagliflozin, a sodium-glucose co-transporter 2 inhibitor in normal and ZDF rat plasma.

Aubry AF, Gu H, Magnier R, Morgan L, Xu X, Tirmenstein M, Wang B, Deng Y, Cai J, Couerbe P, and Arnold M

Audio, Transactions of the IRE Profession... 2(12):2001-9 (2010) PMID 21110743

Dapagliflozin is an inhibitor of sodium-glucose co-transporter 2 (SGLT-2) in development for the treatment of Type 2 diabetes. To support toxicology studies, LC-MS/MS methods were developed and validated for the quantitation of dapagliflozin in rat plasma.

DOI: 10.4155/bio.10.139
Version: za2963e q8za6 q8zbf q8zc4 q8zd3 q8ze1 q8zf7 q8zg3
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