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Ongoing purifying selection on intergenic spacers in group A streptococcus

Infection, Genetics and Evolution 11(2):343 (2011) PMID 21115137 PMCID PMC3411356

Research highlights ▶ We examine variation in genes and linked spacers in group A Streptococcus (GAS). ▶ Spacers show signs of past purifying selection, as do nonsynonymous sites in genes. ▶ There are potentially many slightly deleterious variants in GAS populations.

DOI: 10.1016/j.meegid.2010.11.005