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Chlorosulfolipids: structure, synthesis, and biological relevance.

D Karl DK Bedke and Christopher D CD Vanderwal

Nat Prod Rep 28(1):15-25 (2011) PMID 21125121

Chlorosulfolipids have been isolated from freshwater algae and from toxic mussels. They appear to have a structural role in algal membranes and have been implicated in Diarrhetic Shellfish Poisoning. Further fascinating aspects of these compounds include their stereochemically complex polychlorinated structures and the resulting strong conformational biases, and their poorly understood (yet surely compelling) biosynthesis. Discussions of each of these topics and of efforts in structural and stereochemical elucidation and synthesis are the subject of this Highlight.

DOI: 10.1039/c0np00044b
Version: za2963e q8za5 q8zb0 q8zc4 q8zd2 q8ze4 q8zf2 q8zg5
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