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Differences in the fractional abundances of carbohydrates of natural and recombinant human tissue factor.

Jolanta J Krudysz-Amblo, Mark E ME Jennings, Dwight E DE Matthews, Kenneth G KG Mann, and Saulius S Butenas

ACTA-BIOENERG 1810(4):398-405 (2011) PMID 21172408

Tissue factor (TF) is a single polypeptide integral membrane glycoprotein composed of 263 residues and is essential to life in its role as the initiator of blood coagulation. Previously we have shown that the activity of the natural placental TF (pTF) and the recombinant TF (rTF) from Sf9 insect cells is different (Krudysz-Amblo, J. et al (2010) J. Biol. Chem. 285, 3371-3382).

DOI: 10.1016/j.bbagen.2010.12.003
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