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Short-term administration of uridine increases brain membrane phospholipid precursors in healthy adults: a 31-phosphorus magnetic resonance spectroscopy study at 4T.

Nivedita Agarwal, Young-Hoon Sung, J Eric Jensen, Grace Dacunha, David Harper, David Olson, and Perry F Renshaw

Bipolar Disord 12(8):825-33 (2010) PMID 21176029

  Altered metabolism of membrane phospholipids has been implicated in bipolar disorder. In humans, uridine is an important precursor of cytidine diphosphate (CDP)-choline, which plays a critical role in phospholipid synthesis and is currently being evaluated as a potential treatment for bipolar depression.

DOI: 10.1111/j.1399-5618.2010.00884.x
Version: za2963e q8za4 q8zb9 q8zce q8zd4 q8ze4 q8zfd q8zg9
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