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C. elegans star proteins, GLD-1 and ASD-2, regulate specific RNA targets to control development.

Min-Ho MH Lee and Tim T Schedl

Adv Exp Med Biol (2010) PMID 21189689

A comprehensive understanding of the C. elegans STAR proteins GLD-1 and ASD-2 is emerging from a combination of studies. Those employing genetic analysis reveal in vivo function, others involving biochemical approaches pursue the identification of mRNA targets through which these proteins act. Lastly, mechanistic studies provide the molecular pathway of target mRNA regulation.

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