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Changes of brain structure and function in ADHD children.

Ming-guo MG Qiu, Zhang Z Ye, Qi-yu QY Li, Guang-jiu GJ Liu, Bing B Xie, and Jian J Wang

Brain Topogr 24(3-4):243-52 (2011) PMID 21191807

To explore the changes of brain structure and function in attention-deficit/hyperactivity disorder (ADHD), fifteen ADHD patients (inattention subtype) and 15 normal control participants were recruited, the brain structure and function of these subjects were investigated by combining structural magnetic resonance imaging (MRI), diffusion tensor imaging and resting-state functional MRI. The results showed that ADHD patients had a significant decrease in the volume of the white matter (P = 0.04), and a trend toward decreased volume of brain structures except for the putamen and globus pallidus. The visualization of statistical difference maps of the cortical thickness showed that ADHD patients had focal thinning in bilateral frontal regions and the right cingulate cortex (P 

DOI: 10.1007/s10548-010-0168-4
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