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Plasma Plasmodium falciparum histidine-rich protein-2 concentrations do not reflect severity of malaria in Papua new guinean children.

Laurens L Manning, Moses M Laman, Danielle D Stanisic, Anna A Rosanas-Urgell, Cathy C Bona, David D Teine, Peter P Siba, Ivo I Mueller, and Timothy M E TM Davis

Audio, Transactions of the IRE Professiona... 52(4):440-6 (2011) PMID 21216895

In areas of unstable malaria transmission, plasma Plasmodium falciparum histidine-rich protein 2 (PfHRP-2) concentrations parallel total parasite biomass and thus infection severity. However, where transmission is more intense, plasma PfHRP-2 might not reliably predict complications and mortality.

DOI: 10.1093/cid/ciq105
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