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Admission visfatin levels predict pancreatic and peripancreatic necrosis in acute pancreatitis and correlate with clinical severity.

Andreas A Schäffler, Okka-Wilkea OW Hamer, Judith J Dickopf, Andrea A Goetz, Karin K Landfried, Markus M Voelk, Hans H Herfarth, Andrea A Kopp, Christa C Buechler, Jürgen J Schölmerich, and Tanja T Brünnler

Am J Gastroenterol 106(5):957-67 (2011) PMID 21245835

Adipocytes of peripancreatic and intrapancreatic adipose tissue secret adipocytokines such as leptin, adiponectin, and resistin. For resistin, a role as an early predictor of peripancreatic necrosis and clinical severity in acute pancreatitis has been reported. It was the aim of this study to investigate whether the adipocytokine visfatin is able to serve as an early marker predicting peripancreatic necrosis and clinical severity.

DOI: 10.1038/ajg.2010.503
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