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An Efficient Synthesis of de novo Imidates via Aza-Claisen Rearrangements of N-Allyl Ynamides.

Kyle A Dekorver, Troy D North, and Richard P Hsung

Synlett 2010(16):2397-2402 (2010) PMID 21278848 PMCID PMC3027154

A novel thermal 3-aza-Claisen rearrangement of N-allyl ynamides for the synthesis of α-allyl imidates is described. Also, a sequential aza-Claisen, Pd-catalyzed Overman rearrangement is described for the synthesis of azapine-2-ones.

DOI: 10.1055/s-0030-1258544
Version: za2963e q8za7 q8zb0 q8zc2 q8zda q8zef q8zf6 q8zg1
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