Advanced search×

Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males.

Anna R AR Giuliano, Joel M JM Palefsky, Stephen S Goldstone, Edson D ED Moreira, Mary E ME Penny, Carlos C Aranda, Eftyhia E Vardas, Harald H Moi, Heiko H Jessen, Richard R Hillman, Yen-Hwa YH Chang, Daron D Ferris, Danielle D Rouleau, Janine J Bryan, J Brooke JB Marshall, Scott S Vuocolo, Eliav E Barr, David D Radley, Richard M RM Haupt, and Dalya D Guris

N Engl J Med 364(5):401-11 (2011) PMID 21288094 PMCID PMC3495065

Infection with human papillomavirus (HPV) and diseases caused by HPV are common in boys and men. We report on the safety of a quadrivalent vaccine (active against HPV types 6, 11, 16, and 18) and on its efficacy in preventing the development of external genital lesions and anogenital HPV infection in boys and men.

DOI: 10.1056/NEJMoa0909537
Version: za2963e q8za4 q8zbb q8zc0 q8zd2 q8zec q8zf0 q8zgc
View PDF

Similar articles you may find interesting…

  1. Oral immunization with an attenuated salmonella gallinarum mutant as a fowl typhoid vaccine with a live adjuvant strain secreting the B subu...
    Byung Woo Jeon, Rahul M Nandre, and John Hwa Lee

    BMC Vet Res 9(1):96 (2013) PMID 23647814

    Plasma IgG, intestinal secretory IgA (sIgA), and cell-mediated responses were significantly induced after a boost inoculation with a mixture of JOL916 and JOL1229, and significant reductions in the mortality of chickens challenged with a wild-type SG strain were observed in the immunized groups. The...
    PDF not found
  2. A novel synthetic (poly)glycerolphosphate-based anti-staphylococcal conjugate vaccine.
    Quanyi Chen, Jay Dintaman, and Clifford M Snapper

    Infect Immun (2013) PMID 23649092

    We developed a synthetic method for producing glycerol phosphoramidites to create a covalent 10-mer of (poly)glycerolphosphate for potential use in a conjugate vaccine. We initially demonstrate that intact Staphylococcus aureus elicits murine CD4+ T cell-dependent (poly)glycerolphosphate-specific Ig...
    Buy PDF
  3. A method for rapid production of heteromultimeric protein complexes in plants: assembly of protective bluetongue virus-like particles.
    Eva C Thuenemann, Ann E Meyers, and George P Lomonossoff

    Plant Biotechnol J (2013) PMID 23647743

    Plant expression systems based on nonreplicating virus-based vectors can be used for the simultaneous expression of multiple genes within the same cell. They therefore have great potential for the production of heteromultimeric protein complexes. This work describes the efficient pla...
    Buy PDF