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In vitro bioaccessibility and gut biotransformation of polyphenols present in the water-insoluble cocoa fraction.

Vincenzo V Fogliano, Maria Laura ML Corollaro, Paola P Vitaglione, Aurora A Napolitano, Rosalia R Ferracane, Fabiano F Travaglia, Marco M Arlorio, Adele A Costabile, Annett A Klinder, and Glenn G Gibson

Mol Nutr Food Res (2011) PMID 21294250

Cocoa, especially the water-insoluble cocoa fraction (WICF), is a rich source of polyphenols. In this study, sequential in vitro digestion of the WICF with gastrointestinal enzymes as well as its bacterial fermentation in a human colonic model system were carried out to investigate bioaccessibility and biotransformation of WICF polyphenols, respectively.

DOI: 10.1002/mnfr.201000360
Version: za2963e q8zae q8zb1 q8zc9 q8zde q8ze1 q8zf4 q8zg2
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