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Accreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast.

Mark J MJ Wehrum, Irina A IA Buhimschi, Carolyn C Salafia, Stephen S Thung, Mert O MO Bahtiyar, Erica F EF Werner, Katherine H KH Campbell, Christine C Laky, Anna K AK Sfakianaki, Guomao G Zhao, Edmund F EF Funai, and Catalin S CS Buhimschi

Am J Obstet Gynecol 204(5):411.e1-411.e11 (2011) PMID 21316642 PMCID PMC3136625

We sought to characterize serum angiogenic factor profile of women with complete placenta previa and determine if invasive trophoblast differentiation characteristic of accreta, increta, or percreta shares features of epithelial-to-mesenchymal transition.

Copyright © 2011 Elsevier Ltd. All rights reserved.

DOI: 10.1016/j.ajog.2010.12.027
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