It has been argued that emotion, pain and cognitive control are functionally segregated in distinct subdivisions of the cingulate cortex. However, recent observations encourage a fundamentally different view. Imaging studies demonstrate that negative affect, pain and cognitive control activate an overlapping region of the dorsal cingulate--the anterior midcingulate cortex (aMCC). Anatomical studies reveal that the aMCC constitutes a hub where information about reinforcers can be linked to motor centres responsible for expressing affect and executing goal-directed behaviour. Computational modelling and other kinds of evidence suggest that this intimacy reflects control processes that are common to all three domains. These observations compel a reconsideration of the dorsal cingulate's contribution to negative affect and pain.
Pigment epithelium-derived factor (PEDF) was discovered as a neurotrophic factor secreted by retinal pigment epithelial cells. A decade later, it re-emerged as a powerful angiogenesis inhibitor guarding ocular function. Since then, significant advances were made identifying PEDF's mechanisms, target...
A systematic study of the radiative proton capture reaction for all stable
nickel isotopes is presented. The results were obtained using 2.0 - 6.0 MeV
protons from the 11 MV tandem Van de Graaff accelerator at the University of
Notre Dame. The \gamma-rays were detected by the NSCL SuN detector util...
We have used soft x-ray magnetic diffraction at the Fe3+ L2,3 edges to
Examine to what extent the Dzyaloshinsky-Moriya interaction in Ba3NbFe3Si2O14
Influences its low temperature magnetic structure. A modulated component of the
Moments along the c-axis is present, adding to the previously proposed...
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