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Genome sequences of two Staphylococcus aureus ovine strains that induce severe (strain O11) and mild (strain O46) mastitis.

Caroline Le Maréchal, David Hernandez, Jacques Schrenzel, Sergine Even, Nadia Berkova, Richard Thiéry, Eric Vautor, J Ross Fitzgerald, Patrice François, and Yves Le Loir

J Bacteriol 193(9):2353-4 (2011) PMID 21398544

Staphylococcus aureus is a major etiological agent of mastitis in ruminants. We report here the genome sequences of two ovine strains that were isolated from gangrenous (strain O11) and subclinical (strain O46) ewe mastitis. Both strains belong to the same clonal complex. Despite this close genotypic relationship, the two isolates were shown to reproducibly induce highly divergent types of infections, either severe (O11) or mild (O46) mastitis, in an experimental ewe model.

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