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Montelukast, a cysteinyl leukotriene receptor-1 antagonist, attenuates chronic brain injury after focal cerebral ischaemia in mice and rats.

Rui R Zhao, Wen-Zhen WZ Shi, Yong-Mei YM Zhang, San-Hua SH Fang, and Er-Qing EQ Wei

J Pharm Pharmacol 63(4):550-7 (2011) PMID 21401607

Previously we demonstrated the neuroprotective effect of montelukast, a cysteinyl leukotriene receptor-1 (CysLT(1) ) antagonist, on acute brain injury after focal cerebral ischaemia in mice. In this study, we have determined its effect on chronic brain injury after focal cerebral ischaemia in mice and rats.

DOI: 10.1111/j.2042-7158.2010.01238.x
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