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Mean platelet volume and risk of bronchopulmonary dysplasia and intraventricular hemorrhage in extremely preterm infants.

Carlo C Dani, Chiara C Poggi, Jacopo J Barp, Elettra E Berti, and Giulia G Fontanelli

Am J Perinatol 28(7):551-6 (2011) PMID 21404166

The possible correlation between the mean platelet volume (MPV) and the occurrence of bronchopulmonary dysplasia (BPD) and intraventricular hemorrhage (IVH) in a cohort of preterm infants was assessed. We studied infants with gestational age 11 fL increases (relative risk 1.40, 95% confidence interval 1.08 to 1.80) the risk of developing BPD. MPV was similar in infants with or without IVH. We concluded that high MPV in the first days of life is a risk factor for the development of BPD in extremely preterm infants. This might be because high MPV could favor inflammatory and oxidative lung damage. On the contrary, our data indicate that MPV is not associated with the development of IVH in our population.

DOI: 10.1055/s-0031-1274503
Version: za2963e q8zab q8zb8 q8zc6 q8zd1 q8ze6 q8zf0 q8zgf
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