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Priapism in the United States: the changing role of sickle cell disease

Kristin L Chrouser, Onaopemipo B Ajiboye, Tolulope A Oyetunji, and David C Chang

Am J Surg 201(4):7 (2011) PMID 21421100

Background: Few patients with priapism require inpatient management unless they are refractory to intracavernosal therapy. Their risk factors and outcomes are poorly characterized. Methods: This is a retrospective analysis of the Nationwide Inpatient Sample (1998-2006). Priapism patients were identified and analyzed over time by age, race, sickle-cell disease diagnosis, drug abuse, and penile operations. Results: A total of 4,237 hospitalizations for priapism were identified (30% white, 61.1% black, and 6.3% Hispanics). There was an increasing incidence of priapism over time, concentrated in the middle-age group. There were 1,776 patients (41.9%) with diagnoses of sickle-cell disease, with decreasing proportions over time. Drug abuse was reported in 7.9%. Conclusions: Inpatient diagnoses of priapism are increasing over time with relatively constant numbers of sickle-cell disease patients, suggesting rising nonhematologic causes of priapism. One theory is that increasing use of aggressive therapies for erectile dysfunction might play a role, especially when combined with drug abuse.

Copyright © 2011 Elsevier Ltd. All rights reserved.

DOI: 10.1016/j.amjsurg.2010.03.017
Version: za2963e q8za5 q8zbf q8zcd q8zdc q8zea q8zff q8zg5

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