We compared efficacy of combined treatment of males with anogenital warts given intramuscular cycloferon or cycloferon electrophoresis. Patients with manifest HPV infection (n=107) were divided into two groups. Group 1 (n=72) received intramuscular cycloferon (2 ml 12.5% solution each other day for 10 days), group 2 (n=35) received cycloferon electrophoresis on genital region (2 ml 12.5% solution daily in 1-2 days, 5 injections). Measurements were made of local cytokines in urethral secretion, IFN-alpha, IFN-gamma, lactoferrin, sexual hormones (estradiol and testosterone) in blood serum before and after treatment. Focal immunophysiotherapy with cycloferon in combined treatment of males with anogenital warts vs intramuscular cycloferon treatment reduces recurrence rate 2 times, has no negative effect on serum level of sexual hormones, a course dose and duration of immunotherapy decreased 2-fold, is well tolerated, is not painful. Cycloferon electrophoresis has a more potent effect on improvement of local immunity. Thus, local immunophysiotherapy with cycloferon can be a method of choice in the treatment of manifest HPV infection in males.
We assessed attitudes to medicines, HIV treatments and antiretroviral-based prevention in a national, online survey of 1,041 Australian gay men (88.3 % HIV-negative and 11.7 % HIV-positive). Multivariate analysis of variance was used to identify the effect of HIV status on attitudes. HIV-negative...
We report the experimental finding of a new surface treatment that
Systematically improves the quality factor of niobium radio frequency cavities
For particle acceleration. A combination of annealing in a partial pressure of
Nitrogen and subsequent electropolishing of the niobium cavity surface lead...
Natural philosophy necessarily combines the process of scientific observation
with an abstract (and usually symbolic) framework, which provides a logical
structure to the development of a scientific theory. The metaphysical
underpinning of science includes statements about the process of science
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