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Genotoxic assessment on river water using different biological systems

Emilene Arusievicz Nunes, Clarice Torres de Lemos, Léia Gavronski, Tiago Nunes Moreira, Nânci CD Oliveira, and Juliana da Silva

Chemosphere 84(1):7 (2011) PMID 21435689

This paper reports genotoxicity and toxicity data in water samples collected in Sinos River, an important water course in the hydrographic region of Guaiba Lake, Rio Grande do Sul State, south of Brazil. This river is exposed to intense anthropic influence by numerous shoes, leather, petrochemical, and metallurgy industries. Water samples were collected at two moments (winter 2006 and spring 2006) at five sites of Sinos River and evaluated using in vitro V79 Chinese hamster lung fibroblasts (cytotoxicity, comet assay and micronucleus test) and Allium cepa test (toxicity and micronucleus test). Comet and micronucleus tests revealed that water samples collected exerted cytotoxic, toxic, genotoxic and mutagenic effects. The results showed the toxic action of organic and inorganic agents found in the water samples in all sites of Sinos River, for both data collections. The main causes behind pollution were the domestic and industrial toxic discharges. The V79 and A. cepa tests were proved efficient to detect toxicity and genotoxicity caused by complex mixtures. This study also showed the need for constant monitoring in sites with strong environmental degradation caused by industrial discharges and urban sewages.

Copyright © 2011 Elsevier Ltd. All rights reserved.

DOI: 10.1016/j.chemosphere.2011.02.085
Version: za2963e q8zae q8zb5 q8zcb q8zdf q8ze3 q8zfe q8zg7

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