## Pathophysiology of medication overuse headache: insights and hypotheses from preclinical studies.

Medication overuse headache (MOH) is a clinical concern in the management of migraine headache. MOH arises from the frequent use of medications used for the treatment of a primary headache. Medications that can cause MOH include opioid analgesics as well as formulations designed for the treatment of migraine, such as triptans, ergot alkaloids, or drug combinations that include caffeine and barbiturates.

DOI: 10.1177/0333102411402367
Version: za2963e q8zab q8zb0 q8zc4 q8zd4 q8ze4 q8zf4 q8zga

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