Sulodexide reduces senescence-related changes in human endothelial cells.
Med Sci Monit 17(4):CR222-6 (2011) PMID 21455109
Senescent endothelial cells acquire functional properties that make the vascular wall more prone to atherosclerotic changes. We tested whether senescence of the endothelial cells maintained in in vitro culture can be moderated by their simultaneous exposure to sulodexide.
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