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Plasma clusterin and the risk of Alzheimer disease.

Elisabeth M C Schrijvers, Peter J Koudstaal, Albert Hofman, and Monique M B Breteler

JAMA 305(13):1322-6 (2011) PMID 21467285

Variants in the clusterin gene are associated with the risk of Alzheimer disease (AD) and clusterin levels have been found to be increased in brain and cerebrospinal fluid of patients with AD. Plasma clusterin was reported to be associated with brain atrophy, baseline disease severity, and rapid clinical progression in patients with AD.

DOI: 10.1001/jama.2011.381
Version: za2963e q8za9 q8zbc q8zc7 q8zd7 q8zea q8zf1 q8zg5
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