Advanced search×

Sperm DNA fragmentation and oxidation are independent of malondialdheyde.

Reprod Biol Endocrinol (2011) PMID 21492479

There is clinical evidence to show that sperm DNA damage could be a marker of sperm quality and extensive data exist on the relationship between DNA damage and male fertility status. Detecting such damage in sperm could provide new elements besides semen parameters in diagnosing male infertility. We aimed to assess sperm DNA fragmentation and oxidation and to study the association between these two markers, routine semen parameters and malondialdehyde formation.

DOI: 10.1186/1477-7827-9-47
Version: za2963e q8zaf q8zb2 q8zce q8zda q8ze4 q8zf5 q8zg5

Similar articles you may find interesting…

  1. A label-free amplified fluorescence DNA detection based on isothermal circular strand-displacement polymerization reaction and graphene oxid...

    Analyst (2013) PMID 23671905

    A label-free fluorescent DNA biosensor has been presented based on isothermal circular strand-displacement polymerization reaction (ICSDPR) combined with graphene oxide (GO) binding. The proposed method is simple and cost-effective with a low detection limit of 4 pM, which compares f...
  2. Retaining cytotoxic activity of anthrapyridone CO1 against multidrug resistant cells is related to the ability to induce concomitantly apopt...

    J Pharm Pharmacol 65(6):855-67 (2013) PMID 23647679

    The effect of anthrapyridone compound CO1 retaining cytotoxic activity against multidrug resistant (MDR) tumour cells on inducing cell death of the sensitive leukaemia HL60 cell line and its MDR sublines (HL60/VINC and HL60/DOX) was examined. The effects of CO1 and th...
  3. How does pheomelanin synthesis contribute to melanomagenesis?: Two distinct mechanisms could explain the carcinogenicity of pheomelanin synt...

    Bioessays (2013) PMID 23650156

    We reported that melanoma risk in redheads is linked not only to pale skin, but also to the synthesis of the pigment - called pheomelanin - that gives red hair its color. We demonstrated that pheomelanin synthesis is associated with increased oxidative stress in the skin, yet we have not uncovered t...