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Non-myeloablative conditioning with allogeneic hematopoietic cell transplantation for the treatment of high-risk acute lymphoblastic leukemia.

Ron R Ram, Rainer R Storb, Brenda M BM Sandmaier, David G DG Maloney, Ann A Woolfrey, Mary E D ME Flowers, Michael B MB Maris, Ginna G GG Laport, Thomas R TR Chauncey, Thoralf T Lange, Amelia A AA Langston, Barry B Storer, and George E GE Georges

Haematologica 96(8):1113-20 (2011) PMID 21508120

Allogeneic hematopoietic cell transplantation is a potentially curative treatment for patients with acute lymphoblastic leukemia. However, the majority of older adults with acute lymphoblastic leukemia are not candidates for myeloablative conditioning regimens. A non-myeloablative preparative regimen is a reasonable treatment option for this group. We sought to determine the outcome of non-myeloablative conditioning and allogeneic transplantation in patients with high-risk acute lymphoblastic leukemia.

DOI: 10.3324/haematol.2011.040261
Version: za2963e q8za8 q8zbb q8zc6 q8zd1 q8ze2 q8zf7 q8zg1
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