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Translational control by the eukaryotic ribosome.

Ivan I Topisirovic and Nahum N Sonenberg

Cell 145(3):333-4 (2011) PMID 21529706

The ribosome plays a universally conserved role in catalyzing protein synthesis. Kondrashov et al. (2011) now provide evidence that the loss of function of ribosomal protein L38 in mice leads to a selective reduction in the translation of Hox mRNAs, thus suggesting that ribosomal proteins play a critical role during embryonic development.

Copyright © 2011 Elsevier Ltd. All rights reserved.

DOI: 10.1016/j.cell.2011.04.006
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