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The basis of differential responses to folic acid supplementation.

Ioana I Cotlarciuc, Toby T Andrew, Tracy T Dew, Gail G Clement, Raj R Gill, Gabriela G Surdulescu, Roy R Sherwood, and Kourosh R KR Ahmadi

J Nutrigenet Nutrigenomics 4(2):99-109 (2011) PMID 21625172

Elevated levels of total homocysteine (tHcy) are associated with an increased risk of many common diseases. Supplementation with folic acid has been shown to significantly reduce tHcy levels. We used the classical twin model to partition the variability in changes in plasma tHcy levels through folic acid supplementation into genetic, environmental, and confounding epidemiological factors.

DOI: 10.1159/000327768
Version: za2963e q8zac q8zbd q8zc0 q8zdf q8zef q8zfa q8zgb

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