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Role of the SaeRS two-component regulatory system in Staphylococcus epidermidis autolysis and biofilm formation.

Qiang Q Lou, Tao T Zhu, Jian J Hu, Haijing H Ben, Jinsong J Yang, Fangyou F Yu, Jingran J Liu, Yang Y Wu, Adrien A Fischer, Patrice P Francois, Jacques J Schrenzel, and Di D Qu

BMC Microbiol (2011) PMID 21702925

Staphylococcus epidermidis (SE) has emerged as one of the most important causes of nosocomial infections. The SaeRS two-component signal transduction system (TCS) influences virulence and biofilm formation in Staphylococcus aureus. The deletion of saeR in S. epidermidis results in impaired anaerobic growth and decreased nitrate utilization. However, the regulatory function of SaeRS on biofilm formation and autolysis in S. epidermidis remains unclear.

DOI: 10.1186/1471-2180-11-146
Version: za2963e q8zae q8zbe q8zc9 q8zd8 q8zeb q8zf4 q8zgd
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