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- This Paper
Analysis of interleukin-10 gene polymorphisms and hepatitis C susceptibility in Pakistan.
Muhammad Sohail MS Afzal, Sadia S Tahir, Amna A Salman, Tahir Ahmed TA Baig, Talha T Shafi, Najm Us Sahar Sadaf NU Zaidi and Ishtiaq I Qadri
pubmed 5(6):473-9 1 Jun 2011
PMID 21727647
Hepatitis C virus (HCV) commonly causes a chronic infection but few of patients are able to clear the virus naturally. Interleukin-10 (IL-10) is an anti-inflammatory cytokine that can suppress the immune response against HCV. Interindividual variations in IL-10 production are genetically contributed by polymorphisms within the IL-10 promoter region. This study aimed to investigate the association of the IL-10 gene promoter -1082 G/A, -819 C/T, and -592 C/A polymorphisms with HCV infection susceptibility in Pakistani individuals.
DOI:
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DOI:
Version: za2963e q8za9 q8zb8 q8zc7 q8zd3 q8zeb q8zfb q8zg1