High dose of dietary resveratrol enhances insulin sensitivity in healthy rats but does not lead to metabolite concentrations effective for SIRT1 expression.
Mol Nutr Food Res 55(8):1197-206 (2011) PMID 21732533
trans-Resveratrol has been shown to improve insulin sensitivity and to enhance cellular glucose uptake. Evidence from recent studies indicates that these effects depend on SIRT1-pathways.
DOI: 10.1002/mnfr.201100292
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