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Sequences that direct subcellular traffic of the Drosophila methoprene-tolerant protein (MET) are located predominantly in the PAS domains

Molecular and Cellular Endocrinology 345(1-2):16 (2011) PMID 21745535

Highlights ► We ask what elements affect subcellular traffic of methoprene-tolerant protein (MET). ► We identify mosaic of both nuclear localization signals and nuclear export signals. ► Subcellular localization of MET depends on combined contribution of various signals. ► The activity of PAS-B nuclear localization signal is controlled by juvenile hormone.

DOI: 10.1016/j.mce.2011.06.035