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Modeling Down syndrome screening performance using first-trimester serum markers.

Ultrasound Obstet Gynecol 38(2):134-9 (2011) PMID 21800388

To evaluate the modeled predictive value of three current screening markers (pregnancy-associated plasma protein-A (PAPP-A), free β-human chorionic gonadotropin (free β-hCG), and nuchal translucency (NT)) and four potential screening markers (a disintegrin and metalloprotease 12 (ADAM12), total hCG, placental protein 13 (PP13), and placental growth factor (PlGF)) for Down syndrome using different screening strategies.

DOI: 10.1002/uog.8881
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