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Expression of insulin-like growth factor II mRNA-binding protein 3 in human esophageal adenocarcinoma and its precursor lesions.

Wei W Feng, Zhongren Z Zhou, Jeffrey H JH Peters, Thaer T Khoury, Qihui Q Zhai, Qiying Q Wei, Camtu D CD Truong, Sonya Wei SW Song, and Dongfeng D Tan

Arch Pathol 135(8):1024-31 (2011) PMID 21809994

Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is an oncofetal protein highly expressed in fetal tissue and malignant tumors but only rarely within adult benign tissues. The expression of IMP3 in esophageal adenocarcinoma (EAC) and its precursor lesions including distinctive type Barrett mucosa (BM, intestinal metaplasia) and esophageal columnar dysplasia (ECD) is largely unknown.

DOI: 10.5858/2009-0617-OAR2
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