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Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects.

Hyo-Soon HS Jeong, Seung Hoon SH Lee, Hye-Young HY Yun, Kwang Jin KJ Baek, Nyoun Soo NS Kwon, Kyoung-Chan KC Park, and Dong-Seok DS Kim

J Biomed Sci (2011) PMID 21838918

Sphingosylphosphorylcholine (SPC) acts as a potent lipid mediator and signaling molecule in various cell types. In the present study, we investigated the effects of SPC on melanogenesis and SPC-modulated signaling pathways related to melanin synthesis.

DOI: 10.1186/1423-0127-18-55
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