Variant antigens expressed on the surface of parasitized red blood cells (pRBCs) are important virulence factors of malaria parasites. Whereas Plasmodium falciparum erythrocyte membrane proteins 1 (PfEMP1) are responsible for sequestration of mature parasites, little is known about putative ligands mediating cytoadherence to host receptors in other Plasmodium species. Candidates include members of the pir superfamily found in the human parasite Plasmodium vivax (vir), in the simian pathogen Plasmodium knowlesi (kir) and in the rodent malarias Plasmodium yoelii (yir), Plasmodium berghei (bir) and Plasmodium chabaudi (cir). The aim of this study was to reveal a potential involvement of cir genes in P. chabaudi sequestration.
We study admissibility of inference rules and unification with parameters in
Transitive modal logics (extensions of K4), in particular we generalize various
Results on parameter-free admissibility and unification to the setting with
Specifically, we give a characterization of projectiv...
We explore an approach for studying epistasis
In humans using a Drosophila melanogaster model of neonatal diabetes mellitus.
Expression of mutant preproinsulin, hINSC96Y, in the eye imaginal disc mimics
The human disease activating conserved cell stress response pathways leading to
Cell death and re...
The homogeneous state of a granular flow of smooth inelastic hard spheres or
disks described by the Enskog-Boltzmann kinetic equation is analyzed. The
granular gas is fluidized by the presence of a random force and a drag force.
The combined action of both forces, that act homogeneously on the gran...
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