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Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer.

Da D Yang, Sofia S Khan, Yan Y Sun, Kenneth K Hess, Ilya I Shmulevich, Anil K AK Sood, and Wei W Zhang

JAMA 306(14):1557-65 (2011) PMID 21990299

Attempts to determine the clinical significance of BRCA1/2 mutations in ovarian cancer have produced conflicting results.

DOI: 10.1001/jama.2011.1456
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