Homology and concerted evolution at the alpha 1 and alpha 2 loci of human alpha-globin.
The identical structure of two racially distinct alpha 1-globin alleles and the high degree of homology between the alpha 1- and alpha 2-globin loci indicate that mechanisms exist for suppression of allelic polymorphisms and for exchange of genetic information within the alpha-globin gene complex.
DOI: 10.1038/290026a0
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