In this study on twenty-two adult subjects, the effectiveness of Parodontax dentifrice was compared to a control dentifrice on gingival bleeding parameters. The periodontal probe bleeding index of Ainamo and Bay, modified to evaluate slight and moderate bleeding, was used to evaluate efficacy. There was no significant difference between the two groups at baseline. After four weeks, Parodontax dentifrice produced a significant decrease (p < 0.01) in bleeding on probing compared both to baseline (p < 0.01) and to the control group (p < 0.05), and an increase (p < 0.05) in the number of sites with no bleeding compared to the control dentifrice. The control had no significant decrease in bleeding on probing from baseline to four weeks. The number of bleeding sites were significantly reduced in the Parodontax dentifrice group from baseline to week four (p < 0.001), and there was no significant statistical change in the number of bleeding sites for the control group. The Parodontax dentifrice group bleeding sites at four weeks were significantly lower than the control group (p < 0.05).