Hemoglobin Old Dominion/Burton-upon-Trent, beta 143 (H21) His-->Tyr, codon 143 CAC-->TAC--a variant with altered oxygen affinity that compromises measurement of glycated hemoglobin in diabetes mellitus: structure, function, and DNA sequence.
G E GE Elder,
T R TR Lappin,
A B AB Horne,
V F VF Fairbanks,
R T RT Jones,
P C PC Winter,
B N BN Green,
J D JD Hoyer,
T M TM Reynolds,
D T DT Shih,
D J DJ McCormick,
K S KS Kubik,
B J BJ Madden,
C G CG Head,
D D Harvey and
N B NB Roberts
Mayo Clin Proc 73(4):321-8 (1998)
PMID 9559035
To determine the nature and characteristics of a unique hemoglobin variant that causes a spurious increase in glycated hemoglobin (HbA1c).
DOI:
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