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Andrew D Johnson   Andrew Johnson   Andrew C Johnson   Andrew J Johnson   Andrew M Johnson   Andrew A Johnson   Andrew L Johnson   Andrew S Johnson  
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  1. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake.
    Toshiko Tanaka, Julius S Ngwa, ... Jennifer A Nettleton

    Am J Clin Nutr (2013) PMID 23636237

    A variant in the chromosome 19 locus (rs838145) was associated with higher carbohydrate (β ± SE: 0.25 ± 0.04%; P = 1.68 × 10(-8)) and lower fat (β ± SE: -0.21 ± 0.04%; P = 1.57 × 10(-9)) consumption. A candidate gene in this region, fibroblast growth factor 21 (FGF21), encodes a fibroblast g...
  2. Cemented hemiarthroplasty or hip replacement for intracapsular neck of femur fracture? A comparison of 7732 matched patients using national ...
    Simon S Jameson, Deborah Lees, ... Mike R Reed

    Injury (2013) PMID 23618782

    BACKGROUND: The treatment of choice for intracapsular neck of femur (NOF) fractures in younger, more active patients remains unknown. Some surgeons advocate total hip replacement (THR). AIM: This study aimed to compare complications following THR and hemiarthroplasty using the Hospit...
  3. CVD of pure copper films from novel iso-ureate complexes.
    Alexander M AM Willcocks, Thomas T Pugh, ... Andrew J AJ Kingsley

    Dalton Trans 42(15):5530-41 (2013) PMID 23425976

    We report the synthesis and characterisation of a new family of copper(i) metal precursors based around alkoxy-N,N'-di-alkyl-ureate ligands, and their subsequent application in the production of pure copper thin films. The molecular structure of the complexes bis-copper(i)(methoxy-N,N'-di-isopropylur...
  4. Repercussions of occult malignancy - An etiologic basis for rheumatic disease.
    Andrew Kelly AK Johnson

    Med Hypotheses 80(4):447-51 (2013) PMID 23357672

    Paraneoplastic syndromes and infection are known causes of autoimmunity, but the etiology of most autoimmune syndromes remains unknown. If the immune system can effectively fight malignant cell lines, it is likely that many potential tumors are controlled before becoming clinically apparent. This phe...
  5. MULTILATERAL CONTRACTING AND PREVENTION.
    Brandon Pope, Abhijit Deshmukh, ... James Rohack

    Health Econ (2013) PMID 23554156

    We consider an insurer contracting with a consumer and a provider. We focus on the trade-off between ex ante moral hazard and insurance, and consider both consumer and provider incentives in the insurer's contracting problem in the presence of unobservable preventive efforts. We study two cases of p...
  6. A Systems Biology Framework Identifies Molecular Underpinnings of Coronary Heart Disease.
    Tianxiao Huan, Bin Zhang, ... Daniel Levy

    Arterioscler Thromb Vasc Biol (2013) PMID 23539213

    Our network-driven integrative analysis not only identified CHD-related genes, but also defined network structure that sheds light on the molecular interactions of genes associated with CHD risk....
  7. Gene Expression Signatures of Coronary Heart Disease.
    Roby Joehanes, Saixia Ying, ... Peter J Munson

    Arterioscler Thromb Vasc Biol (2013) PMID 23539218

    Two bioinformatically defined groups of genes show consistent associations with CHD. Our findings are consistent with the hypotheses that hematopoesis is upregulated in CHD, possibly reflecting a compensatory mechanism, and that innate immune activity is disrupted in CHD or altered by its treatment....
  8. Statistical model for prediction of hearing loss in patients receiving Cisplatin chemotherapy.
    Andrew A Johnson, Sergey S Tarima, ... Christina L CL Runge

    JAMA Otolaryngology - Head & Neck Surgery 139(3):256-64 (2013) PMID 23429908

    IMPORTANCE This statistical model might be used to predict cisplatin-induced hearing loss, particularly in patients undergoing concomitant radiotherapy. OBJECTIVE To create a statistical model based on pretreatment hearing thresholds to provide an individual probability for hearing l...
  9. The origins and drivers of insulin resistance.
    Andrew M F AM Johnson and Jerrold M JM Olefsky

    Cell 152(4):673-84 (2013) PMID 23415219

    Obesity-induced insulin resistance is the major determinant of metabolic syndrome, which precedes the development of type 2 diabetes mellitus and is thus the driving force behind the emerging diabetes epidemic. The precise causes of insulin resistance are varied, and the relative imp...
  10. Predicting positive margins in resection of cutaneous melanoma of the head and neck.
    J Jared JJ Christophel, Andrew K AK Johnson, ... Paul A PA Levine

    Laryngoscope 123(3):683-8 (2013) PMID 23404736

    In this large series of head and neck melanomas excised using National Comprehensive Cancer Network-recommended margins, histopathologic margin status could be predicted based on age but not on lesion characteristics. This finding is surprising given the published data showing that melanoma in situ...