To address these challenges we introduce here methods for local ancestry inference which leverage the structure of linkage disequilibrium in the ancestral population (LAMP-LD), and incorporate the constraint of Mendelian segregation when inferring local ancestry in nuclear family trios (LAMP-HAP). O...

We present an alternative to MCMC based on Sequential Monte Carlo (SMC). We develop an extension of classical SMC based on partially ordered sets, and show how to apply this framework-which we refer to as PosetSMC-to phylogenetic analysis. We provide a theoretical treatment of PosetSMC and also pres...

We consider the problem of reconstruction of sparse signals in compressed sensing. In particular, we introduce a novel iterative algorithm based on graph-based decoding of low-density parity-check codes which possesses desirable properties like good performance, low complexity and running time, and...

This paper presents a methodology for confidence assessment in model-based structural health monitoring, using the domain of fatigue crack growth analysis. Several models - finite element model, crack growth model, surrogate model, etc. - are connected through a Bayes network that aids in model calib...

In the tridentate ligand 2,6-bis(1-benzyl-1H-1,2,3-triazol-4-yl)pyridine, C(23)H(19)N(7), both sets of triazole N atoms are anti with respect to the pyridine N atom, while in the copper complex aqua[2,6-bis(1-benzyl-1H-1,2,3-triazol-4-yl)pyridine](pyridine)(tetrafluoroborato)copper(II) tetrafluorobo...

We performed a whole-genome association study on alpha (alpha), beta (beta), and theta (theta) EEG power in a Native American cohort of 322 individuals to take advantage of the genetic and environmental homogeneity of this population isolate. We identified three genes (SGIP1, ST6GALNAC3, and UGDH) w...

A diacetylenic molecular hinge bearing two ethynyltriphenylene units (1) has been synthesized. Evidence from (1)H NMR and variable temperature NMR (VT-NMR) of 1 in comparison to model compounds bearing only one triphenylene unit suggests that there is an equilibrium between the open conformer and th...

In cross-validation experiments on two benchmark datasets from the Catalytic Site Atlas and CATRES resources containing a total of 437 manually curated enzymes spanning 487 SCOP families, Discern increases catalytic site recall between 12-20% over methods that combine information from both sequence...

We first present an $O(N^{2})$ Distributed algorithm for discovering the shortest CDC-path between given Source and destination. This improves the running time of the $O(N^{3})$ Centralized algorithm of Ahuja et al. for finding the minimum-weight CDC-path. Our second result is a generalized $t$-span...

We analyse the Theoretical aspects of the problem and provide guarantees about the lifetime Achievable. We introduce a number of practical algorithms and analyse their Significance. The main contribution is a novel linear programming based Algorithm which provides near-optimal lifetime. Through exte...

We present an analytical and empirical study of the statistical power of such methods. We thereby aim to provide quantitative guidelines for researchers wishing to make a limited number of SNPs available publicly without compromising subjects' privacy....